Hydrogenation of nitriles

The hydrogenation of nitriles to primary amines is a key industrial process with broad applications in pharmaceuticals, fine chemicals, and plastics manufacturing. In this catalytic reaction, the cyano group (C≡N) is converted into a primary amino group (–CH₂–NH₂) through the addition of hydrogen:

R–C≡N + 2 H₂ → R–CH₂–NH₂

Nickel- and copper-based catalysts are highly effective for this transformation. Optimized reaction conditions enable high selectivity for primary amines at moderate temperatures and pressures, making the process economically attractive for large-scale production. This approach is particularly suitable for producing fatty amines from renewable raw materials.

We recommend NiSat, HyMax, and HySat catalysts: highly selective nickel- and copper-based catalysts specifically designed for the hydrogenation of nitriles to primary amines.

Ideal applications include the pharmaceutical industry, basic chemical production, plastics, and fine and specialty chemicals.